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Fentanyl Module

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  1. Introduction
    Introduction
  2. What is Fentanyl and Why Is It so Deadly?
  3. Medical Use
  4. How does Fentanyl Affect the Body?
  5. Summary
  6. Effects
    What are the Effects of Fentanyl?
  7. Respiratory Depression
  8. Rapid Overdose
  9. Long-term effects
  10. How can Fentanyl Impact People With Other Medical Conditions?
  11. Summary
  12. Overdose
    What are the Signs of a Fentanyl Overdose?
  13. Is Fentanyl Overdose Reversible?
  14. Action Plan!
  15. Routes of Administration
  16. Summary
  17. Risks
    General Risks
  18. Risk Philosophy
  19. Polysubstance Use and Fentanyl Use
  20. How to Decrease your Risk
  21. Drug Checking
  22. Activity
  23. Summary
  24. Treatment
    Substitution Treatment
  25. Heroin-Assisted Treatment
  26. Resources for Risk Management
  27. Summary
  28. Last Remarks!
Fentanyl Module Polysubstance Use and Fentanyl Use
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Lesson 19 of 28
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Polysubstance Use and Fentanyl Use


The risk of overdose increases if you use fentanyl with:

  • Alcohol, benzodiazepines such as Xanax, Valium, Ativan
  • Stimulants such as cocaine
  • Other opioids like heroin

These substances can intensify fentanyl side effects, putting extra stress on organs such as your heart and lungs, which can make it hard to manage clinically in case of an overdose.

What is Polysubstance Abuse? | Drug and Alcohol Rehab | Beaches